Ron Stoop Lab    

What are the physiological mechanisms at the basis of fear and anxiety ? How is it that certain noises in the middle of the night can scare us, while a similar sound during daytime has no such effect? We meanwhile know that one region in the brain is particularly involved in our anxiety and fear responses: the amygdala, a cluster of nuclei situated in the temporal obe, anterior to the hippocampus. My group studies the regulation of these responses by the amygdala in a comparative way between humans and rodents, preferably the rat, a very interactive companion with an important social life that resembles us in many aspects.

consists of a combination of electrophysiological and optogenetics methods applied in vitro and in vivo, both in rodents and human patients. For the in vitro part, we have established in Cery a laboratory with various electrophysiological set-ups to record neurophysiological signalling in slices of rat and in tissue removed from human patients by our partners in neurosurgery. For the in vivo part, we have access to an on-site center that allows evaluation of animal behavior with a multitude of behavioral tests. To keep up with the latest developments we maintain various international collaborations and to translate our findings we collaborate both with clinical and industry partners.

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The new Centre for Psychiatric Neurosciences (CNP) on the Cery Campus